Fixturin
Trade name: Fixtrin
Small moleculeapproved
Approved
Jun 15, 2020
Fixturin is a synthetic small-molecule fixture drug used to validate CDEK query behavior end-to-end. — ChEMBL
Clinical trial activity
2 trials · 1 clinical orgs · 1 marketing orgs
Phase 1
1
Phase 2
0
Phase 3
1
Phase 4
0
Earliest trial started Mar 1, 2015 (NCT90000001)
Timeline
2010s
- Jan 1, 2015
Fixture Pharmaceuticals — Earliest Phase 1 Sponsor(trial)
- Jan 1, 2015
Fixture Pharmaceuticals — IND Organization
- Jan 1, 2015
Fixture Pharmaceuticals — IND Organization
- Jan 1, 2019
Fixture Pharmaceuticals — Earliest Phase 3 Sponsor(trial)
2020s
- Jun 15, 2020
Fixture Pharmaceuticals — Earliest FDA Approval
- Jun 15, 2020
Fixture Pharmaceuticals — NDA Organization
- Jul 1, 2020
Evidence of US Marketing
- Jul 1, 2020
Fixture Pharmaceuticals — Marketing Organization
Indications
Approved for
Mechanism of action
- Fixture Target AlphaINHIBITOR
Inhibits Fixture Target Alpha, blocking downstream signaling.
Approval history
- marketedJul 1, 2020
- approvedPriority reviewJun 15, 2020
Chemistry & pharmacology
Loading structure…
SMILES
CC(C)CC1=CC=C(C=C1)C(C)C(=O)O- Mol. weight
- 206.28 g/mol
- Lipinski Ro5
- Pass
- Rule of 3
- Yes
- Chirality
- None
- Inorganic
- No
- Polymer
- No
- Class
- Analgesic
- Delivery
- Oral tablet
- Availability
- Prescription
- Multi-specific
- No (Mono-specific)
Oral
Yes
Parenteral
No
Topical
No
First in class
Sources
- ChEMBLCHEMBL900001 ↗
- FDANDA900001 ↗
Also known as
- Fixtrin
- Fixturin
Clinical trials
| NCT ID | Phase | Start date | Sponsor(s) |
|---|---|---|---|
| NCT90000002 | Phase 3 | Apr 1, 2019 | Fixture Pharmaceuticals |
| NCT90000001 | Phase 1 | Mar 1, 2015 | Fixture Pharmaceuticals |
Showing 2 of 2 trials
Page 1 / 1
Organizations
Research & Development (1)
| Organization | Org type | Trials | As lead sponsor | Phases | Earliest year |
|---|---|---|---|---|---|
| Fixture Pharmaceuticals | For profit | 2 | 0 | 1 | 2015 |
1 organizations
Page 1 / 1
Marketing (3)
| Organization | Org type | Relationship | Date |
|---|---|---|---|
| Fixture Pharmaceuticals | For profit | IND | Jan 1, 2015 |
| Fixture Pharmaceuticals | For profit | NDA | Jun 15, 2020 |
| Fixture Pharmaceuticals | For profit | MKTG | Jul 1, 2020 |